[1]刘晨,丁长河*,金少举,等.鸟苷酸发酵工艺优化[J].中国调味品,2018,(7):15-20.[doi:10.3969/j.issn.1000-9973.2018.07.004]
　LIU Chen,DING Chang-he*,JIN Shao-ju,et al.Optimization of the Technology of GMPs Fermentation[J].CHINA CONDIMENT,2018,(7):15-20.[doi:10.3969/j.issn.1000-9973.2018.07.004]
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鸟苷酸发酵工艺优化()
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《中国调味品》[ISSN:1000-9973/CN:23-1299/TS]

卷:
期数:
2018年7期
页码:
15-20
栏目:
出版日期:
2018-07-01

文章信息/Info

Title:
Optimization of the Technology of GMPs Fermentation
文章编号:
1000-9973(2018)07-0015-06
作者:
刘晨1; 丁长河1*; 金少举2; 陈复生1; 杜娟1
(1.河南工业大学食品学院,河南 郑州 450000; 2.河南省南街村(集团)
Author(s):
LIU Chen1; DING Chang-he1*; JIN Shao-ju2; CHEN Fu-sheng1; DU Juan1
(1.College of Food Science,Henan University of Technology,Zhengzhou 450000,China;2.Henan Nanjiecun (Group) Co., Ltd.,Luohe 462000,China)
关键词:
鸟苷; 酸发酵; 工艺
Keywords:
guanylate; fermentation; technology
分类号:
TS201.56
DOI:
10.3969/j.issn.1000-9973.2018.07.004
文献标志码:
A
摘要:
鸟苷酸具有显著的增鲜功能、辅助抗肿瘤、提高机体免疫力以及调节机体营养代谢等作用，因而广泛应用于食品和医药领域。发酵以枯草芽孢杆菌变异菌株为出发菌株，在单因素试验基础上，采用正交试验对发酵培养基及发酵条件对鸟苷产量的影响进行研究，结果表明，葡萄糖添加量为10%，发酵温度为36 ℃，发酵时间72 h时，鸟苷产量可达到10.6 g/L，较优化前提高了71%。
Abstract:
Guanylate is widely used in food and medicine because of its remarkable function of increasing fresh, assisting in anti-tumor, improving immunity and regulating nutrient metabolism of the body. The Bacillus subtilis variant strain is used as the starting strain for fermentation. Based on the single factor experiment, the effects of fermentation medium and fermentation conditions on the yield of guanosine are studied by orthogonal test.The results show that the additive amount of glucose is 10%, the fermentation temperature is 36 °C, the fermentation time is 72 h, the guanosine production reaches 10.6 g/L, which is 71% higher than that before optimization.

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更新日期/Last Update: 2018-08-08